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It is a sedating antihistamine (H1-blocker) with appreciable anticholinergic, sedative, and antiemetic results and a few local anesthetic properties. Promethazine has been used as an antihistamine in some prescription cough and cold products. Promethazine is also used as an antiemetic in surgical care settings to deal with or stop or deal with post-operative nausea/vomiting and may be used to treat motion illness. If parenteral use of promethazine is critical, the preferred route of administration is by deep intramuscular injection. Where can i buy promethazine real. Nci Drug Dictionary promethazine Use of the intravenous route may be associated with significant opposed reactions such as extreme tissue necrosis and gangrene. Tell your physician or pharmacist in case you are taking other merchandise similar to opioid pain or cough relievers , alcohol, marijuana , drugs for sleep or anxiety , muscle relaxants , or other antihistamines . This research demonstrates that promethazine promethazine in overdose causes CNS depression, tachycardia and delirium, the final being the most important by way of morbidity and useful resource requirement. There was a consistent affiliation between reported dose and the probability of delirium, not just for promethazine alone but also with co-ingestants. promethazine Mail order prescription promethazine. Monitor for indicators and signs of potential tissue injury together with burning or ache at the website of injection, phlebitis, swelling, and blistering.The use of promethazine by way of intraarterial administration or subcutaneous administration is contraindicated as a result of such dangers.Proper intravenous administration is nicely usually tolerated; however, because of the increased risk of extreme tissue necrosis and injury, the popular route of administration is deep intramuscular injection.Cholestatic jaundice from phenothiazines is usually thought of a hypersensitivity response. promethazine Drug promethazine Overdose Buy promethazine ferrara. Contraindications additionally include comatose patients and patients with lower respiratory tract signs. Promethazine has substantial anticholinergic results and a worsening of symptoms could also be seen in patients with bladder obstruction, GI obstruction or ileus, benign prostatic hypertrophy, or urinary retention. These precautions are most important when utilizing antihistamines from the ethanolamine or phenothiazine group. In basic, the elderly are typically extra prone to the anticholinergic results of drugs since there's a decline in endogenous cholinergic activity that occurs with age.
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